Host Microbe Symbiosis in Gut Immunity
Ramnik Joseph Xavier, MD, PhD
Director, Center for Computational and Integrative Biology
Kurt Isselbacher Professor of Medicine, Harvard Medical School
Core Institute Member, Broad Institute of MIT and Harvard
Biography：
Elected Member, American Association of Physicians
Abstract:
Recent advances have provided substantial insight into the maintenance of mucosal immunity. Cellular programs responsible for intestinal homeostasis use diverse intracellular and intercellular networks to promote immune tolerance, inflammation or epithelial restitution. Complex interfaces integrate local host and microbial signals to activate appropriate effector programs selectively and even drive plasticity between these programs. In addition, genetic studies and mouse models have emphasized the role of genetic predispositions and how they affect interactions with microbial and environmental factors, leading to the host-commensal relationship.
Time: Jun 19th 2018, 10:30 - 11:30
Venue: Medical Science Building, Room B-323（医学科学楼B323）
Host: Prof. Michael Q. Zhang
